fatty acid synthesis — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T7529	Yamogenin		Others
	Yamogenin is a diastereomer of diosgenin, which we have identified as the compound responsible for the anti-hyperlipidemic effect of fenugreek.		Others
T11267	FASN-IN-1	TVB-2460	Fatty Acid Synthase
	FASN-in-1 is an effective, specific inhibitor of fatty acid synthase (FASN), a compound specifically designed to target and inhibit the activity of the enzyme involved in fatty acid synthesis, potentially disrupting fatt...		Fatty Acid Synthase
T27460	GSK2324	GSK-2324,GSK 2324	FXR
	GSK2324 is a potent FXR agonist for the treatment of NAFLD by controlling hepatic lipids through reduced uptake and selective reduction of fatty acid synthesis.		FXR
T13802	Oleamide	Oleic acid amide	Others , Endogenous Metabolite
	Oleamide (Oleic acid amide) is an endogenous fatty acid amide and can be used in the synthesis of de novo in the mammalian nervous system.		Others , Endogenous Metabolite
T3P2904	α-Linolenic acid	Alpha-Linolenic Acid,Linolenic acid	Akt , PI3K
	α-Linolenic acid (Alpha-Linolenic Acid) is an essential fatty acid belonging to the omega-3 fatty acids group. It is highly concentrated in certain plant oils and has been reported to inhibit the synthesis of prostagland...		Akt , PI3K
TN7251	Olivetol Dimethyl Ether	1,3-dimethoxy-5-pentylbenzene	Others
	Olivetol Dimethyl Ether is a monoacylglycerol with analgesic activity and potential anti-inflammatory activity that inhibits fatty acid synthesis.		Others
T9209	PF-05221304	STAT5 Inhibitor III,NSC 170984,R 6238,,Clesacostat	Acetyl-CoA Carboxylase
	PF-05221304 (NSC-170984) is an orally active, liver-targeted inhibitor of acetyl-CoA carboxylase (ACC), a rate-limiting enzymes for fatty acid synthesis.		Acetyl-CoA Carboxylase
T11590	(-)-Hydroxycitric acid	Garcinia acid	ATP Citrate Lyase
	(-)-Hydroxycitric acid (Garcinia acid) (Garcinia acid) is the principal acid of fruit rinds of Garcinia cambogia. It is a potent and competitive inhibitor of ATP citrate lyase. (-)-Hydroxycitric acid suppresses fatty aci...		ATP Citrate Lyase
T2S0164	Ethyl palmitate	Palmitic acid ethyl ester,Ethyl cetylate,Ethyl hexadecanoate	Others
	Ethyl palmate (palmitic acid ethyl ester) is a type of fatty acid ethyl ester (FAEE). After human subjects consumed alcohol, its synthesis was higher than other FAEEs. It can be used as a hair and skin conditioner.		Others
T4535	Etomoxir sodium salt	(R)-Etomoxir sodium salt,Na salt,Etomoxir	Apoptosis , Others
	Etomoxir sodium salt ((R)-Etomoxir sodium salt) is a carnitine palmitoyltransferase 1a (CPT-1a) inhibitor that blocks fatty acid synthesis. Etomoxir sodium salt has antitumor activity.		Apoptosis , Others
T1165	Ethionamide	Bayer 5312,2-ethylthioisonicotinamide,Ethinamide	Dehydrogenase , CAT , Antibacterial , Antibiotic
	Ethionamide (2-ethylthioisonicotinamide) is a nicotinamide derivative, with antibacterial activity, used to treat tuberculosis. Although the exact mechanism of action of ethionamide is unknown, it may inhibit the synthes...		Dehydrogenase , CAT , Antibacterial , Antibiotic
T4740	Elaidic acid	trans-Oleic Acid	Endogenous Metabolite
	Elaidic acid (trans-Oleic Acid) is the 9-trans isomer of oleic acid. It is a monounsaturated trans-fatty acid which can be found in partially hydrogenated cooking oils. In human platelets incubated with arachidonic acid,...		Endogenous Metabolite
T4309	CIL56	CA3	Ferroptosis , ROS
	CIL56 (CA3) is a small molecule that induces cellular ferroptosis through the production of iron-dependent reactive oxygen species (ROS). It also induces accumulation of long-chain saturated, monounsaturated, and polyuns...		Ferroptosis , ROS
T0894	Thiamine hydrochloride	Vitamin B1,Vitamin B1 hydrochloride,Thiamine HCl,Thiamine chloride hydrochloride	Apoptosis , HBV , Endogenous Metabolite
	Thiamine hydrochloride (Vitamin B1) is the hydrochloride salt form of thiamine, a vitamin essential for aerobic metabolism, cell growth, transmission of nerve impulses and acetylcholine synthesis. Upon hydrolysis, Thiami...		Apoptosis , HBV , Endogenous Metabolite
T17180	TVB-3166		Apoptosis , Others , Fatty Acid Synthase
	TVB-3166 induces apoptosis and inhibits in-vivo xenograft tumor growth. TVB-3166 is a reversible and selective fatty acid synthase inhibitor (IC50s: 42 nM and 81 nM for biochemical FASN and cellular palmitate synthesis,...		Apoptosis , Others , Fatty Acid Synthase
T4129	Arachidonic acid	Immunocytophyte,arachidonate,Immunocytophyt,Vevodar	Others , Endogenous Metabolite
	Arachidonic acid (Immunocytophyte) is an unsaturated, essential fatty acid. It is found in animal and human fat as well as in the liver, brain, and glandular organs, and is a constituent of animal phosphatides. It is for...		Others , Endogenous Metabolite
T36831	9-Oxononanoic Acid	9-ONA	Phospholipase , CPT
	9-Oxononanoic Acid is an oxidized fatty acid, formed by the autoxidation of linoleic acid, which enhances phospholipase A2 (PLA2) activity and increases the production of thromboxane B2 in isolated human plasma.9-Oxonona...		Phospholipase , CPT
T77513	2-Chlorophenylboronic acid		FAAH
	2-Chlorophenylboronic acid is a monohalogenated phenylboronic acid, which is an important pharmaceutical intermediate and is widely used in the synthesis of new drugs.2-Chlorophenylboronic acid has an inhibitory effect o...		FAAH
T17181	TVB-3664		Fatty Acid Synthase
	TVB-3664 significantly decreases tubulin palmitoylation and mRNA expression. TVB-3664 is a reversible and highly bioavailable fatty acid synthase inhibitor (IC50: 18 nM and 12 nM for human and mouse cell palmitate synthe...		Fatty Acid Synthase
T6480	D-Pantothenic acid	vitamin B5,pantothenate	Others
	D-Pantothenic acid (vitamin B5) is a water-soluble vitamin ubiquitously found in plants and animal tissues with an antioxidant property. D-Pantothenic acid is a component of coenzyme A (CoA) and a part of the vitamin B2 ...		Others